U-Blot® Acetyl eIF5A/eIF5A2 (Lys47) Polyclonal Antibody

Name: U-Blot® Acetyl eIF5A/eIF5A2 (Lys47) Polyclonal Antibody
SKU: WP0268
Availability: InStock

$288.00

Size:50μL

SKU: WP0268-50

Catalog No.: WP0268

Specification: 50μL/100μL

Stock: In stock

U-Blot® Acetyl eIF5A/eIF5A2 (Lys47) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,

Product Overview

Catalog No.: WP0268
SKU: WP0268-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: eIF5A2
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): 17kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Acetyl
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human eIF5A around the Acetylation site of Lys47. AA range:11-60
Sequence: --
Specificity: Acetyl-eIF5A/eIF5A2 (K47) Polyclonal Antibody detects endogenous levels of eIF5A/eIF5A2 protein only when acetylated at K47.
Gene Name: EIF5A2
Protein Name: Eukaryotic translation initiation factor 5A-2
Other Name: EIF5A2;Eukaryotic translation initiation factor 5A-2;eIF-5A-2;eIF-5A2;Eukaryotic initiation factor 5A isoform 2
Organism-1: Human
Gene ID-1: 56648
SwissProt-1: Q9GZV4
Organism-2: Mouse
Gene ID-2: 208691
SwissProt-2: Q8BGY2
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Nucleus, nuclear pore complex . Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. .