U-Blot® Ku-70 (Acetyl Lys539) Polyclonal Antibody

Name: U-Blot® Ku-70 (Acetyl Lys539) Polyclonal Antibody
SKU: WP0279
Availability: InStock

$288.00

Size:50μL

SKU: WP0279-50

Catalog No.: WP0279

Specification: 50μL/100μL

Stock: In stock

U-Blot® Ku-70 (Acetyl Lys539) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP0279
SKU: WP0279-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Ku70/XRCC6
Reactivity: Human,Rat,Mouse,
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 70kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Acetyl
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K539.
Sequence: --
Specificity: Acetyl-Ku-70 (K539) Polyclonal Antibody detects endogenous levels of Ku-70 protein only when acetylated at K539.
Gene Name: XRCC6
Protein Name: X-ray repair cross-complementing protein 6
Other Name: XRCC6;G22P1;X-ray repair cross-complementing protein 6;5'-deoxyribose-5-phosphate lyase Ku70;5'-dRP lyase Ku70;70 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase II 70 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC75;CTCBF;DNA repair protein XRCC6;Lupus Ku autoantigen protein p70;Ku70;Thyroid-lupus autoantigen;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 6
Organism-1: Human
Gene ID-1: 2547
SwissProt-1: P12956
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P23475
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome .