U-Blot® PARP-1 (Acetyl-Lys521) Polyclonal Antibody

Name: U-Blot® PARP-1 (Acetyl-Lys521) Polyclonal Antibody
SKU: WP0338
Availability: InStock

$288.00

Size:50μL

SKU: WP0338-50

Catalog No.: WP0338

Specification: 50μL/100μL

Stock: In stock

U-Blot® PARP-1 (Acetyl-Lys521) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP0338
SKU: WP0338-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PARP
Reactivity: Human:K521,Mouse:K520,Rat:K521
Application: WB,ELISA
MW(Calculated): 113kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Acetyl
Modification site: --
Recommended Dilution Ratio: WB 1:1000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized Acetyl peptide derived from human PARP-1. at AA range: K521
Sequence: --
Specificity: This antibody detects endogenous levels of PARP-1 at Human:K521;Mouse:K520;Rat:K521, It doesn't reacte with total protein.
Gene Name: PARP1 ADPRT PPOL
Protein Name: PARP-1
Other Name: Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1;
Organism-1: Human
Gene ID-1: 142
SwissProt-1: P09874
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P11103
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .