U-Blot® EF-1 α1/2 (Acetyl Lys146) rabbit pAb

Name: U-Blot® EF-1 α1/2 (Acetyl Lys146) rabbit pAb
SKU: WP0378
Availability: InStock

$288.00

Size:50μL

SKU: WP0378-50

Catalog No.: WP0378

Specification: 50μL/100μL

Stock: In stock

U-Blot® EF-1 α1/2 (Acetyl Lys146) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP0378
SKU: WP0378-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EF-1 α1/2
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 51kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Acetyl
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000;ELISA 1:5000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human EF-1 α1/2 (Acetyl Lys146)
Sequence: --
Specificity: This antibody detects endogenous levels of Human,Mouse,Rat EF-1 α1/2 (Acetyl Lys146)
Gene Name: EEF1A1 EEF1A EF1A LENG7
Protein Name: EF-1 α1/2 (Acetyl Lys146)
Other Name: Elongation factor 1-alpha 1;EF-1-alpha-1;Elongation factor Tu;EF-Tu;Eukaryotic elongation factor 1 A-1;eEF1A-1;Leukocyte receptor cluster member 7;
Organism-1: Human
Gene ID-1: 1915
SwissProt-1: P68104;Q05639;Q5VTE0
Organism-2: Mouse
Gene ID-2: 13627
SwissProt-2: P10126
Organism-3: Rat
Gene ID-3: 171361
SwissProt-3: P62630
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Nucleus, nucleolus . Cell membrane . Colocalizes with DLC1 at actin-rich regions in the cell periphery (PubMed:19158340). Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens (PubMed:8650580). Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B (PubMed:26497934). .