U-Blot® IBTK Polyclonal Antibody

Name: U-Blot® IBTK Polyclonal Antibody
SKU: WP0581
Availability: InStock

$268.00

Size:50μL

SKU: WP0581-50

Catalog No.: WP0581

Specification: 50μL/100μL

Stock: In stock

U-Blot® IBTK Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],

Product Overview

Catalog No.: WP0581
SKU: WP0581-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IBTK
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 148kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 410-490
Sequence: --
Specificity: IBTK Polyclonal Antibody detects endogenous levels of protein.
Gene Name: IBTK BTKI KIAA1417
Protein Name: Inhibitor of Bruton tyrosine kinase (IBtk)
Other Name: --
Organism-1: Human
Gene ID-1: 25998
SwissProt-1: Q9P2D0
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6ZPR6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein. Translocates to the plasma membrane upon IgM stimulation.; [Isoform 2]: Nucleus.