U-Blot® CDA7L Polyclonal Antibody

Name: U-Blot® CDA7L Polyclonal Antibody
SKU: WP0601
Availability: InStock

$268.00

Size:50μL

SKU: WP0601-50

Catalog No.: WP0601

Specification: 50μL/100μL

Stock: In stock

U-Blot® CDA7L Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,

Product Overview

Catalog No.: WP0601
SKU: WP0601-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CDA7L
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 49kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 140-220
Sequence: --
Specificity: CDA7L Polyclonal Antibody detects endogenous levels of protein.
Gene Name: CDCA7L HR1 JPO2 R1
Protein Name: Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
Other Name: --
Organism-1: Human
Gene ID-1: 55536
SwissProt-1: Q96GN5
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q922M5
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q4G059
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Nucleus. Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.