U-Blot® ABCA7 Polyclonal Antibody

Name: U-Blot® ABCA7 Polyclonal Antibody
SKU: WP0900
Availability: InStock

$268.00

Size:50μL

SKU: WP0900-50

Catalog No.: WP0900

Specification: 50μL/100μL

Stock: In stock

U-Blot® ABCA7 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP0900
SKU: WP0900-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ABCA7
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 236kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 2050-2130
Sequence: --
Specificity: ABCA7 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: ABCA7
Protein Name: ATP-binding cassette sub-family A member 7 (ABCA-SSN) (Autoantigen SS-N) (Macrophage ABC transporter)
Other Name: --
Organism-1: Human
Gene ID-1: 10347
SwissProt-1: Q8IZY2
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q91V24
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q7TNJ2
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein . Cytoplasm . Cell projection, ruffle membrane . Cell projection, phagocytic cup . Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney (By similarity). .; [Isoform 2]: Cytoplasm . Endoplasmic reticulum . May localize to the endoplasmic reticulum. .