U-Blot® BOK Polyclonal Antibody

Name: U-Blot® BOK Polyclonal Antibody
SKU: WP0922
Availability: InStock

$268.00

Size:50μL

SKU: WP0922-50

Catalog No.: WP0922

Specification: 50μL/100μL

Stock: In stock

U-Blot® BOK Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011],

Product Overview

Catalog No.: WP0922
SKU: WP0922-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BOK
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 23kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90
Sequence: --
Specificity: BOK Polyclonal Antibody detects endogenous levels of protein.
Gene Name: BOK BCL2L9
Protein Name: Bcl-2-related ovarian killer protein (hBOK) (Bcl-2-like protein 9) (Bcl2-L-9)
Other Name: --
Organism-1: Human
Gene ID-1: 666
SwissProt-1: Q9UMX3
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O35425
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q792S6
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion inner membrane . Cytoplasm . Nucleus . Mitochondrion . Endoplasmic reticulum . Mitochondrion outer membrane . Early endosome membrane . Recycling endosome membrane . Nucleus outer membrane . Golgi apparatus, cis-Golgi network membrane . Golgi apparatus, trans-Golgi network membrane . Membrane . Nuclear and cytoplasmic compartments in the early stages of apoptosis and during apoptosis it associates with mitochondria (PubMed:19942931). In healthy cells, associates loosely with the membrane in a hit-and-run mode. The insertion and accumulation on membranes is enhanced through the activity of death signals, resulting in the integration of the membrane-bound protein into the membrane (PubMed:15868100). The transmembrane domain controls subcellular localization; constitutes a tail-anchor. Localizes in early and late endosome upon blocking of apoptosis. Must localize to the mitochondria to induce mitochondrial outer membrane permeabilization and apoptosis (By similarity). .; [Isoform 2]: Membrane . Cytoplasm .