U-Blot® Claudin-4 (phospho Tyr208) Polyclonal Antibody

Name: U-Blot® Claudin-4 (phospho Tyr208) Polyclonal Antibody
SKU: WP10117
Availability: InStock

$288.00

Size:50μL

SKU: WP10117-50

Catalog No.: WP10117

Specification: 50μL/100μL

Stock: In stock

U-Blot® Claudin-4 (phospho Tyr208) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],

Product Overview

Catalog No.: WP10117
SKU: WP10117-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Claudin-4
Reactivity: Human,Rat,Mouse,
Application: IHC,IF,ELISA
MW(Calculated): 22kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 4 around the phosphorylation site of Tyr208. AA range:160-209
Sequence: --
Specificity: Phospho-Claudin-4 (Y208) Polyclonal Antibody detects endogenous levels of Claudin-4 protein only when phosphorylated at Y208.
Gene Name: CLDN4
Protein Name: Claudin-4
Other Name: CLDN4;CPER;CPETR1;WBSCR8;Claudin-4;Clostridium perfringens enterotoxin receptor;CPE-R;CPE-receptor;Williams-Beuren syndrome chromosomal region 8 protein
Organism-1: Human
Gene ID-1: 1364
SwissProt-1: O14493
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O35054
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .