U-Blot® TIP60 (phospho Ser90) Polyclonal Antibody

Name: U-Blot® TIP60 (phospho Ser90) Polyclonal Antibody
SKU: WP10140
Availability: InStock

$288.00

Size:50μL

SKU: WP10140-50

Catalog No.: WP10140

Specification: 50μL/100μL

Stock: In stock

U-Blot® TIP60 (phospho Ser90) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10140
SKU: WP10140-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TIP60
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 59kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Tip60 around the phosphorylation site of Ser90. AA range:56-105
Sequence: --
Specificity: Phospho-TIP60 (S90) Polyclonal Antibody detects endogenous levels of TIP60 protein only when phosphorylated at S90.
Gene Name: KAT5
Protein Name: Histone acetyltransferase KAT5
Other Name: KAT5;HTATIP;TIP60;Histone acetyltransferase KAT5;60 kDa Tat-interactive protein;Tip60;Histone acetyltransferase HTATIP;HIV-1 Tat interactive protein;Lysine acetyltransferase 5;cPLA;2;-interacting protein
Organism-1: Human
Gene ID-1: 10524
SwissProt-1: Q92993
Organism-2: Mouse
Gene ID-2: 81601
SwissProt-2: Q8CHK4
Organism-3: Rat
Gene ID-3: 192218
SwissProt-3: Q99MK2
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Cytoplasm . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Cytoplasm, perinuclear region . Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies (PubMed:11262386). Transiently localizes to kinetochores in early mitosis (PubMed:26829474). Localizes to spindle poles when chromosomes align during metaphase (PubMed:34608293). Localizes in the cytoplasm and nucleus of round spermatids (By similarity). .