U-Blot® HtrA2 (phospho Ser142) Polyclonal Antibody

Name: U-Blot® HtrA2 (phospho Ser142) Polyclonal Antibody
SKU: WP10147
Availability: InStock

$288.00

Size:50μL

SKU: WP10147-50

Catalog No.: WP10147

Specification: 50μL/100μL

Stock: In stock

U-Blot® HtrA2 (phospho Ser142) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WP10147
SKU: WP10147-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HtrA2
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 49kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human HtrA2 (phospho Ser142)
Sequence: --
Specificity: Phospho-HtrA2 (S142) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S142.
Gene Name: HTRA2
Protein Name: Serine protease HTRA2 mitochondrial
Other Name: HTRA2;OMI;PRSS25;Serine protease HTRA2;mitochondrial;High temperature requirement protein A2;HtrA2;Omi stress-regulated endoprotease;Serine protease 25;Serine proteinase OMI
Organism-1: Human
Gene ID-1: 27429
SwissProt-1: O43464
Organism-2: Mouse
Gene ID-2: 64704
SwissProt-2: Q9JIY5
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion intermembrane space. Mitochondrion membrane ; Single-pass membrane protein . Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.; [Isoform 1]: Endoplasmic reticulum .