U-Blot® MARK2 (phospho Thr596) Polyclonal Antibody

Name: U-Blot® MARK2 (phospho Thr596) Polyclonal Antibody
SKU: WP10218
Availability: InStock

$288.00

Size:50μL

SKU: WP10218-50

Catalog No.: WP10218

Specification: 50μL/100μL

Stock: In stock

U-Blot® MARK2 (phospho Thr596) Polyclonal Antibody Learn more

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Background：microtubule affinity regulating kinase 2(MARK2) Homo sapiens This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009],

Product Overview

Catalog No.: WP10218
SKU: WP10218-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MARK2
Reactivity: Human,Mouse,Rat
Application: IF,ELISA
MW(Calculated): 88kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications;
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human MARK2 around the phosphorylation site of Thr596. AA range:562-611
Sequence: --
Specificity: Phospho-MARK2 (T596) Polyclonal Antibody detects endogenous levels of MARK2 protein only when phosphorylated at T596.
Gene Name: MARK2
Protein Name: Serine/threonine-protein kinase MARK2
Other Name: MARK2;EMK1;Serine/threonine-protein kinase MARK2;ELKL motif kinase 1;EMK-1;MAP/microtubule affinity-regulating kinase 2;PAR1 homolog;PAR1 homolog b;Par-1b;Par1b
Organism-1: Human
Gene ID-1: 2011
SwissProt-1: Q7KZI7
Organism-2: Mouse
Gene ID-2: 13728
SwissProt-2: Q05512
Organism-3: Rat
Gene ID-3: 60328
SwissProt-3: O08679
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane; Peripheral membrane protein. Cytoplasm. Lateral cell membrane. Cytoplasm, cytoskeleton. Cell projection, dendrite . Cytoplasm . Phosphorylation at Thr-596 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm.