U-Blot® EDG-1 (phospho Thr236) Polyclonal Antibody

Name: U-Blot® EDG-1 (phospho Thr236) Polyclonal Antibody
SKU: WP10222
Availability: InStock

$288.00

Size:50μL

SKU: WP10222-50

Catalog No.: WP10222

Specification: 50μL/100μL

Stock: In stock

U-Blot® EDG-1 (phospho Thr236) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WP10222
SKU: WP10222-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EDG-1
Reactivity: Human,Mouse,Rat
Application: WB,IF,ELISA
MW(Calculated): --
MW(Observed): 42kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human S1P Receptor EDG1 around the phosphorylation site of Thr236. AA range:206-255
Sequence: --
Specificity: Phospho-EDG-1 (T236) Polyclonal Antibody detects endogenous levels of EDG-1 protein only when phosphorylated at T236.
Gene Name: S1PR1
Protein Name: Sphingosine 1-phosphate receptor 1
Other Name: S1PR1;CHEDG1;EDG1;Sphingosine 1-phosphate receptor 1;S1P receptor 1;S1P1;Endothelial differentiation G-protein coupled receptor 1;Sphingosine 1-phosphate receptor Edg-1;S1P receptor Edg-1;CD antigen CD363
Organism-1: Human
Gene ID-1: 1901
SwissProt-1: P21453
Organism-2: Mouse
Gene ID-2: 13609
SwissProt-2: O08530
Organism-3: Rat
Gene ID-3: 29733
SwissProt-3: P48303
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein. Endosome. Membrane raft. Recruited to caveolin-enriched plasma membrane microdomains in response to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine. Ligand binding leads to receptor internalization.