U-Blot® Flt-1/VEGFR1 (phospho Tyr1213) Polyclonal Antibody

Name: U-Blot® Flt-1/VEGFR1 (phospho Tyr1213) Polyclonal Antibody
SKU: WP10228
Availability: InStock

$288.00

Size:50μL

SKU: WP10228-50

Catalog No.: WP10228

Specification: 50μL/100μL

Stock: In stock

U-Blot® Flt-1/VEGFR1 (phospho Tyr1213) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009],

Product Overview

Catalog No.: WP10228
SKU: WP10228-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Flt-1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 150kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Flt-1 (phospho Tyr1213)
Sequence: --
Specificity: Phospho-Flt-1 (Y1213) Polyclonal Antibody detects endogenous levels of Flt-1 protein only when phosphorylated at Y1213.
Gene Name: FLT1
Protein Name: Vascular endothelial growth factor receptor 1
Other Name: FLT1;FLT;FRT;VEGFR1;Vascular endothelial growth factor receptor 1;VEGFR-1;Fms-like tyrosine kinase 1;FLT-1;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;FLT;Vascular permeability factor receptor
Organism-1: Human
Gene ID-1: 2321
SwissProt-1: P17948
Organism-2: Mouse
Gene ID-2: 14254
SwissProt-2: P35969
Organism-3: Rat
Gene ID-3: 54251
SwissProt-3: P53767
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Endosome. Autophosphorylation promotes ubiquitination and endocytosis.; [Isoform 2]: Secreted .; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Cytoplasm .; [Isoform 6]: Cytoplasm .; [Isoform 7]: Cytoplasm .