U-Blot® MLK3 (phospho Ser674) Polyclonal Antibody

Name: U-Blot® MLK3 (phospho Ser674) Polyclonal Antibody
SKU: WP10231
Availability: InStock

$288.00

Size:50μL

SKU: WP10231-50

Catalog No.: WP10231

Specification: 50μL/100μL

Stock: In stock

U-Blot® MLK3 (phospho Ser674) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10231
SKU: WP10231-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MLK3
Reactivity: Human,Mouse,Rat
Application: WB,IHC
MW(Calculated): 93kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)
Sequence: --
Specificity: Phospho-MLK3 (S674) Polyclonal Antibody detects endogenous levels of MLK3 protein only when phosphorylated at S674.
Gene Name: MAP3K11
Protein Name: Mitogen-activated protein kinase kinase kinase 11
Other Name: MAP3K11;MLK3;PTK1;SPRK;Mitogen-activated protein kinase kinase kinase 11;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase
Organism-1: Human
Gene ID-1: 4296
SwissProt-1: Q16584
Organism-2: Mouse
Gene ID-2: 26403
SwissProt-2: Q80XI6
Organism-3: Rat
Gene ID-3: 309168
SwissProt-3: Q66HA1
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.