U-Blot® EpoR (phospho Tyr426) Polyclonal Antibody

Name: U-Blot® EpoR (phospho Tyr426) Polyclonal Antibody
SKU: WP10234
Availability: InStock

$288.00

Size:50μL

SKU: WP10234-50

Catalog No.: WP10234

Specification: 50μL/100μL

Stock: In stock

U-Blot® EpoR (phospho Tyr426) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

Product Overview

Catalog No.: WP10234
SKU: WP10234-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EpoR
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 55kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human EpoR (phospho Tyr426)
Sequence: --
Specificity: Phospho-EpoR (Y426) Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Y426.
Gene Name: EPOR
Protein Name: Erythropoietin receptor
Other Name: EPOR;Erythropoietin receptor;EPO-R
Organism-1: Human
Gene ID-1: 2057
SwissProt-1: P19235
Organism-2: Mouse
Gene ID-2: 13857
SwissProt-2: P14753
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q07303
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane; Single-pass type I membrane protein.; [Isoform EPOR-S]: Secreted . Secreted and located to the cell surface.