U-Blot® Bamacan (Phospho Ser1083) Polyclonal Antibody

Name: U-Blot® Bamacan (Phospho Ser1083) Polyclonal Antibody
SKU: WP10256
Availability: InStock

$288.00

Size:50μL

SKU: WP10256-50

Catalog No.: WP10256

Specification: 50μL/100μL

Stock: In stock

U-Blot® Bamacan (Phospho Ser1083) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10256
SKU: WP10256-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SMC3
Reactivity: Human,Mouse,Rat
Application: IHC,IF,WB
MW(Calculated): --
MW(Observed): 145kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:50-200;WB 1:500-2000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human Bamacan (Phospho-Ser1083)
Sequence: --
Specificity: This antibody detects endogenous phospho levels of Bamacan (Phospho-Ser1083) at Human:S1083, Mouse:S1083, Rat:S1083
Gene Name: SMC3 BAM BMH CSPG6 SMC3L1
Protein Name: Bamacan (Phospho-Ser1083)
Other Name: Structural maintenance of chromosomes protein 3;SMC protein 3;SMC-3;Basement membrane-associated chondroitin proteoglycan;Bamacan;Chondroitin sulfate proteoglycan 6;Chromosome-associated polypeptide;hCAP;
Organism-1: Human
Gene ID-1: 9126
SwissProt-1: Q9UQE7
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Chromosome, centromere . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. The phosphorylated form at Ser-1083 is preferentially associated with unsynapsed chromosomal regions (By similarity). .