U-Blot® 53BP1 (Phospho Ser1778) rabbit pAb

Name: U-Blot® 53BP1 (Phospho Ser1778) rabbit pAb
SKU: WP10281
Availability: InStock

$288.00

Size:50μL

SKU: WP10281-50

Catalog No.: WP10281

Specification: 50μL/100μL

Stock: In stock

U-Blot® 53BP1 (Phospho Ser1778) rabbit pAb Learn more

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U-Blot® 53BP1 (Phospho Ser1778) rabbit pAb

Product Overview

Catalog No.: WP10281
SKU: WP10281-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: 53BP1
Reactivity: Human,Rat,Mouse,
Application: WB
MW(Calculated): --
MW(Observed): 213kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phosho peptide around human 53BP1 (Ser1778)
Sequence: --
Specificity: This antibody detects endogenous levels of Human 53BP1 (phospho-Ser1778)
Gene Name: TP53BP1
Protein Name: 53BP1 (Ser1778)
Other Name: TP53BP1;Tumor suppressor p53-binding protein 1;53BP1;p53-binding protein 1;p53BP1
Organism-1: Human
Gene ID-1: 7158
SwissProt-1: Q12888
Organism-2: Mouse
Gene ID-2: 27223
SwissProt-2: P70399
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub) and histone H4 dimethylated at 'Lys-20' (H4K20me2), two histone marks that are present at DSBs sites (PubMed:23333306, PubMed:23760478, PubMed:24703952, PubMed:28241136, PubMed:17190600). Associated with kinetochores during mitosis (By similarity). .