U-Blot® IKKε (Phospho Ser172) rabbit pAb

Name: U-Blot® IKKε (Phospho Ser172) rabbit pAb
SKU: WP10380
Availability: InStock

$288.00

Size:50μL

SKU: WP10380-50

Catalog No.: WP10380

Specification: 50μL/100μL

Stock: In stock

U-Blot® IKKε (Phospho Ser172) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009],

Product Overview

Catalog No.: WP10380
SKU: WP10380-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IKKε
Reactivity: Human,Rat,Mouse,
Application: WB
MW(Calculated): --
MW(Observed): 80kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phosho peptide around human IKKε (Ser172)
Sequence: --
Specificity: This antibody detects endogenous levels of Human IKKε (phospho-Ser172)
Gene Name: IKBKE IKKE IKKI KIAA0151
Protein Name: Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Other Name: IKBKE;IKKE;IKKI;KIAA0151;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;I-kappa-B kinase epsilon;IKK-E;IKK-epsilon;IkBKE;Inducible I kappa-B kinase;IKK-i
Organism-1: Human
Gene ID-1: 9641
SwissProt-1: Q14164
Organism-2: Mouse
Gene ID-2: 56489
SwissProt-2: Q9R0T8
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus. Nucleus, PML body . Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent (PubMed:20188669). Located diffusely throughout the cytoplasm but locates to punctate cytoplasmic bodies when coexpressed with TRIM6 (PubMed:24882218). .