- Target
- SGK3
- Reactivity
- Human,Rat,Mouse,
- Application
- WB,IHC
- MW(Calculated)
- --
- MW(Observed)
- 54kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized phosho peptide around human SGK3 (Thr320)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Human SGK3 (phospho-Thr320)
- Gene Name
- SGK3 CISK SGKL
- Protein Name
- Serine/threonine-protein kinase Sgk3
- Other Name
- Serine/threonine-protein kinase Sgk3;Cytokine-independent survival kinase;Serum/glucocorticoid-regulated kinase 3;Serum/glucocorticoid-regulated kinase-like;
- Organism-1
- Human
- Gene ID-1
- 100533105
- SwissProt-1
- Q96BR1
- Organism-2
- Mouse
- Gene ID-2
- 170755
- SwissProt-2
- Q9ERE3
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q8R4V0
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasmic vesicle . Early endosome. Recycling endosome. Endosomal localization is a prerequisite for complete kinase activity. It is essential for its colocalization with the kinase responsible for phosphorylating Ser-486 thus allowing PDPK1 phosphorylation of Thr-320 resulting in complete activation of SGK3. Localized in vesicle-like structures and in the early endosome. Colocalizes with SLC9A3/NHE3 in the recycling endosomes.