- Target
- Rac1/CDC42
- Reactivity
- Human,Mouse,Rat
- Application
- WB,ELISA,IHC
- MW(Calculated)
- 21kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Human,Mouse,Rat Rac1/CDC42 (Phospho Ser71)
- Gene Name
- RAC1 TC25 MIG5
- Protein Name
- Rac1/CDC42 (Phospho Ser71)
- Other Name
- Ras-related C3 botulinum toxin substrate 1;Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1;
- Organism-1
- Human
- Gene ID-1
- 5879
- SwissProt-1
- P63000;P15153;P60763;P60953
- Organism-2
- Mouse
- Gene ID-2
- 19353
- SwissProt-2
- P63001
- Organism-3
- Rat
- Gene ID-3
- 363875
- SwissProt-3
- Q6RUV5
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911). .