U-Blot® CACNA1C (Phospho Ser1981) rabbit pAb

Name: U-Blot® CACNA1C (Phospho Ser1981) rabbit pAb
SKU: WP10685
Availability: InStock

$288.00

Size:50μL

SKU: WP10685-50

Catalog No.: WP10685

Specification: 50μL/100μL

Stock: In stock

U-Blot® CACNA1C (Phospho Ser1981) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：calcium voltage-gated channel subunit alpha1 C(CACNA1C) Homo sapiens This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012],

Product Overview

Catalog No.: WP10685
SKU: WP10685-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CACNA1C
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 244kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CACNA1C (Phospho-Ser1981)
Sequence: --
Specificity: This antibody detects endogenous levels of CACNA1C (Phospho-Ser1981) at Human, Mouse,Rat
Gene Name: CACNA1C CACH2 CACN2 CACNL1A1 CCHL1A1
Protein Name: CACNA1C (Phospho-Ser1981)
Other Name: Voltage-dependent L-type calcium channel subunit alpha-1C;Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle;Voltage-gated calcium channel subunit alpha Cav1.2;
Organism-1: Human
Gene ID-1: 775
SwissProt-1: Q13936
Organism-2: Mouse
Gene ID-2: 12288
SwissProt-2: Q01815
Organism-3: Rat
Gene ID-3: 24239
SwissProt-3: P22002
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Perikaryon . Cell junction, synapse, postsynaptic density membrane . Cell projection, dendrite . Cell membrane, sarcolemma, T-tubule . Colocalizes with ryanodine receptors in distinct clusters at the junctional membrane, where the sarcolemma and the sarcoplasmic reticulum are in close contact. The interaction between RRAD and CACNB2 promotes the expression of CACNA1C at the cell membrane. .