U-Blot® c-Fes (Phospho Tyr713) rabbit pAb

Name: U-Blot® c-Fes (Phospho Tyr713) rabbit pAb
SKU: WP10689
Availability: InStock

$288.00

Size:50μL

SKU: WP10689-50

Catalog No.: WP10689

Specification: 50μL/100μL

Stock: In stock

U-Blot® c-Fes (Phospho Tyr713) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009],

Product Overview

Catalog No.: WP10689
SKU: WP10689-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: c-Fes
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 90kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human c-Fes (Phospho-Tyr713)
Sequence: --
Specificity: This antibody detects endogenous levels of c-Fes (Phospho-Tyr713) at Human, Mouse,Rat
Gene Name: FES FPS
Protein Name: c-Fes (Phospho-Tyr713)
Other Name: FES;FPS;Tyrosine-protein kinase Fes/Fps;Feline sarcoma/Fujinami avian sarcoma oncogene homolog;Proto-oncogene c-Fes;Proto-oncogene c-Fps;p93c-fes
Organism-1: Human
Gene ID-1: 2242
SwissProt-1: P07332
Organism-2: Mouse
Gene ID-2: 14159
SwissProt-2: P16879
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.