U-Blot® BCL-10 (Phospho Ser138) rabbit pAb

Name: U-Blot® BCL-10 (Phospho Ser138) rabbit pAb
SKU: WP10706
Availability: InStock

$288.00

Size:50μL

SKU: WP10706-50

Catalog No.: WP10706

Specification: 50μL/100μL

Stock: In stock

U-Blot® BCL-10 (Phospho Ser138) rabbit pAb Learn more

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Background：This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WP10706
SKU: WP10706-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BCL-10
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 26kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human BCL-10 (Phospho-Ser138)
Sequence: --
Specificity: This antibody detects endogenous levels of BCL-10 (Phospho-Ser138) at Human, Mouse,Rat
Gene Name: BCL10 CIPER CLAP
Protein Name: BCL-10 (Phospho-Ser138)
Other Name: B-cell lymphoma/leukemia 10;B-cell CLL/lymphoma 10;Bcl-10;CARD-containing molecule enhancing NF-kappa-B;CARD-like apoptotic protein;hCLAP;CED-3/ICH-1 prodomain homologous E10-like regulator;CIPER;Cellular homolog of vCARMEN;cCARMEN;Cellular-E10;c-E10;Mammalian CARD-containing adapter molecule E10;mE10;
Organism-1: Human
Gene ID-1: 8915
SwissProt-1: O95999
Organism-2: Mouse
Gene ID-2: 12042
SwissProt-2: Q9Z0H7
Organism-3: Rat
Gene ID-3: 83477
SwissProt-3: Q9QYN5
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, perinuclear region . Membrane raft . Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts. .