- Target
- TPPP
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 24kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human TPPP (Phospho-Ser18)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of TPPP (Phospho-Ser18) at Human, Mouse,Rat
- Gene Name
- TPPP TPPP1
- Protein Name
- TPPP (Phospho-Ser18)
- Other Name
- Tubulin polymerization-promoting protein;TPPP;25 kDa brain-specific protein;TPPP/p25;p24;p25-alpha;
- Organism-1
- Human
- Gene ID-1
- 11076
- SwissProt-1
- O94811
- Organism-2
- Mouse
- Gene ID-2
- 72948
- SwissProt-2
- Q7TQD2
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton . Nucleus . Cytoplasm, cytoskeleton, spindle . Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies (PubMed:15590652, PubMed:17027006). During mitosis, colocalizes with LIMK2 at the mitotic spindle (PubMed:22328514). .