U-Blot® HDAC7A (Phospho Ser486) Rabbit pAb

Name: U-Blot® HDAC7A (Phospho Ser486) Rabbit pAb
SKU: WP10798
Availability: InStock

$288.00

Size:50μL

SKU: WP10798-50

Catalog No.: WP10798

Specification: 50μL/100μL

Stock: In stock

U-Blot® HDAC7A (Phospho Ser486) Rabbit pAb Learn more

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Background：histone deacetylase 7(HDAC7) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10798
SKU: WP10798-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HDAC7
Reactivity: Human,Mouse,Rat
Application: IHC,WB
MW(Calculated): --
MW(Observed): 103kD
Host Species: Rabbit
Isotype: --
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-200
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human HDAC7A (Phospho Ser486)
Sequence: --
Specificity: This antibody detects endogenous levels of HDAC7A (Phospho Ser486) Rabbit pAb at Human, Mouse,Rat
Gene Name: HDAC7 HDAC7A
Protein Name: Histone deacetylase 7 (HD7) (Histone deacetylase 7A) (HD7a)
Other Name: HDAC7;HDAC7A;Histone deacetylase 7;HD7;Histone deacetylase 7A;HD7a
Organism-1: Human
Gene ID-1: 51564
SwissProt-1: Q8WUI4
Organism-2: Mouse
Gene ID-2: 56233
SwissProt-2: Q8C2B3
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q99P96
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Cytoplasm. In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.