U-Blot® FKHRL1 (Phospho Ser318) Rabbit pAb

Name: U-Blot® FKHRL1 (Phospho Ser318) Rabbit pAb
SKU: WP10813
Availability: InStock

$288.00

Size:50μL

SKU: WP10813-50

Catalog No.: WP10813

Specification: 50μL/100μL

Stock: In stock

U-Blot® FKHRL1 (Phospho Ser318) Rabbit pAb Learn more

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Background：forkhead box O3(FOXO3) Homo sapiens This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10813
SKU: WP10813-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: FKHRL1
Reactivity: Human,Mouse
Application: IHC,WB
MW(Calculated): --
MW(Observed): 71kD
Host Species: Rabbit
Isotype: --
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-200
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human FKHRL1 (Phospho Ser318)
Sequence: --
Specificity: This antibody detects endogenous levels of FKHRL1 (Phospho Ser318) Rabbit pAb at Human, Mouse
Gene Name: FOXO3 FKHRL1 FOXO3A
Protein Name: Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)
Other Name: Forkhead box protein O3;AF6q21 protein;Forkhead in rhabdomyosarcoma-like 1;
Organism-1: Human
Gene ID-1: 2309
SwissProt-1: O43524
Organism-2: Mouse
Gene ID-2: 56484
SwissProt-2: Q9WVH4
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Nucleus . Mitochondrion matrix . Mitochondrion outer membrane ; Peripheral membrane protein ; Cytoplasmic side . Retention in the cytoplasm contributes to its inactivation (PubMed:10102273, PubMed:15084260, PubMed:16751106). Translocates to the nucleus upon oxidative stress and in the absence of survival factors (PubMed:10102273, PubMed:16751106). Translocates from the cytosol to the nucleus following dephosphorylation in response to autophagy-inducing stimuli (By similarity). Translocates in a AMPK-dependent manner into the mitochondrion in response to metabolic stress (PubMed:23283301, PubMed:29445193). Serum deprivation increases localization to the nucleus, leading to activate expression of SOX9 and subsequent chondrogenesis (By similarity). .