U-Blot® A Cyclase VIII Polyclonal Antibody

Name: U-Blot® A Cyclase VIII Polyclonal Antibody
SKU: WP10871
Availability: InStock

$268.00

Size:50μL

SKU: WP10871-50

Catalog No.: WP10871

Specification: 50μL/100μL

Stock: In stock

U-Blot® A Cyclase VIII Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10871
SKU: WP10871-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: A Cyclase VIII
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 140kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY8. AA range:591-640
Sequence: --
Specificity: A Cyclase VIII Polyclonal Antibody detects endogenous levels of A Cyclase VIII protein.
Gene Name: ADCY8
Protein Name: Adenylate cyclase type 8
Other Name: ADCY8;Adenylate cyclase type 8;ATP pyrophosphate-lyase 8;Adenylate cyclase type VIII;Adenylyl cyclase 8;AC8;Ca;2+;/calmodulin-activated adenylyl cyclase
Organism-1: Human
Gene ID-1: 114
SwissProt-1: P40145
Organism-2: Mouse
Gene ID-2: 11514
SwissProt-2: P97490
Organism-3: Rat
Gene ID-3: 29241
SwissProt-3: P40146
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Apical cell membrane . Cell junction, synapse . Cell projection, dendrite . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, postsynaptic density . Membrane raft . Membrane, coated pit . Cytoplasmic vesicle, clathrin-coated vesicle membrane . Membrane, caveola . Localized to dendritic arbors (By similarity). Monomeric N-glycosylated species localizes in membrane raft. In contrast, monomeric unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are also localized outside of membrane rafts. Membrane raft localization and integrity is indispensable for CCE-stimulated adenylate cyclase activity (By similarity). .