U-Blot® AKAP 95 Polyclonal Antibody

Name: U-Blot® AKAP 95 Polyclonal Antibody
SKU: WP11000
Availability: InStock

$268.00

Size:50μL

SKU: WP11000-50

Catalog No.: WP11000

Specification: 50μL/100μL

Stock: In stock

U-Blot® AKAP 95 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011],

Product Overview

Catalog No.: WP11000
SKU: WP11000-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: AKAP 95
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 76kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human AKAP8. AA range:331-380
Sequence: --
Specificity: AKAP 95 Polyclonal Antibody detects endogenous levels of AKAP 95 protein.
Gene Name: AKAP8
Protein Name: A-kinase anchor protein 8
Other Name: AKAP8;AKAP95;A-kinase anchor protein 8;AKAP-8;A-kinase anchor protein 95 kDa;AKAP 95
Organism-1: Human
Gene ID-1: 10270
SwissProt-1: O43823
Organism-2: Mouse
Gene ID-2: 56399
SwissProt-2: Q9DBR0
Organism-3: Rat
Gene ID-3: 116633
SwissProt-3: Q63014
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Nucleus matrix . Nucleus, nucleolus . Cytoplasm . Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis. However, mitotic chromatin localization has been questioned. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution. Exhibits partial localization to the nucleolus in interphase, where it colocalizes with UBTF/UBF, suggesting localization to the fibrillary center and/or to the dense fibrillary component. Colocalizes with GJA1 at the nuclear membrane specifically during cell cycle G1/S phase. .