U-Blot® Atg16 Polyclonal Antibody

Name: U-Blot® Atg16 Polyclonal Antibody
SKU: WP11189
Availability: InStock

$268.00

Size:50μL

SKU: WP11189-50

Catalog No.: WP11189

Specification: 50μL/100μL

Stock: In stock

U-Blot® Atg16 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010],

Product Overview

Catalog No.: WP11189
SKU: WP11189-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Atg16
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 70kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from Atg16 . at AA range: 60-140
Sequence: --
Specificity: Atg16 Polyclonal Antibody detects endogenous levels of Atg16 protein.
Gene Name: ATG16L1
Protein Name: Autophagy-related protein 16-1
Other Name: ATG16L1;APG16L;Autophagy-related protein 16-1;APG16-like 1
Organism-1: Human
Gene ID-1: 55054
SwissProt-1: Q676U5
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q8C0J2
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Recruited to omegasomes membranes by WIPI2 (By similarity). Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (By similarity). Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5 (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity). Upon activation of non-canonical autophagy, recruited to single-membrane endolysosomal compartments (PubMed:29317426). .