U-Blot® BIG2 Polyclonal Antibody

Name: U-Blot® BIG2 Polyclonal Antibody
SKU: WP11276
Availability: InStock

$268.00

Size:50μL

SKU: WP11276-50

Catalog No.: WP11276

Specification: 50μL/100μL

Stock: In stock

U-Blot® BIG2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP11276
SKU: WP11276-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BIG2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 210kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ARFGEF2. AA range:1491-1540
Sequence: --
Specificity: BIG2 Polyclonal Antibody detects endogenous levels of BIG2 protein.
Gene Name: ARFGEF2
Protein Name: Brefeldin A-inhibited guanine nucleotide-exchange protein 2
Other Name: ARFGEF2;ARFGEP2;BIG2;Brefeldin A-inhibited guanine nucleotide-exchange protein 2;Brefeldin A-inhibited GEP 2;ADP-ribosylation factor guanine nucleotide-exchange factor 2
Organism-1: Human
Gene ID-1: 10564
SwissProt-1: Q9Y6D5
Organism-2: Mouse
Gene ID-2: 99371
SwissProt-2: A2A5R2
Organism-3: Rat
Gene ID-3: 296380
SwissProt-3: Q7TSU1
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Membrane. Golgi apparatus. Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network . Endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, dendrite . Cytoplasmic vesicle . Cell junction, synapse . Cytoplasm, cytoskeleton . Translocates from cytoplasm to membranes upon cAMP treatment. Localized in recycling endosomes.