U-Blot® CDK5 Activator-binding C48 Polyclonal Antibody

Name: U-Blot® CDK5 Activator-binding C48 Polyclonal Antibody
SKU: WP11563
Availability: InStock

$268.00

Size:50μL

SKU: WP11563-50

Catalog No.: WP11563

Specification: 50μL/100μL

Stock: In stock

U-Blot® CDK5 Activator-binding C48 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

Product Overview

Catalog No.: WP11563
SKU: WP11563-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CDK5 Activator-binding C48
Reactivity: Human,Rat,Mouse,
Application: IHC,IF,ELISA
MW(Calculated): 215kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human CDK5RAP2. AA range:251-300
Sequence: --
Specificity: CDK5 Activator-binding C48 Polyclonal Antibody detects endogenous levels of CDK5 Activator-binding C48 protein.
Gene Name: CDK5RAP2
Protein Name: CDK5 regulatory subunit-associated protein 2
Other Name: CDK5RAP2;CEP215;KIAA1633;CDK5 regulatory subunit-associated protein 2;CDK5 activator-binding protein C48;Centrosome-associated protein 215
Organism-1: Human
Gene ID-1: 55755
SwissProt-1: Q96SN8
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q8K389
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Golgi apparatus . Cytoplasm . Cytoplasm, cytoskeleton . Found in the pericentriolar region adhering to the surface of the centrosome and in the region of the centrosomal appendages. Localizes to microtubule plus ends in the presence of EB1/MAPRE1. Localization to centrosomes versus Golgi apparatus may be cell type-dependent. For instance, in SK-BR-3 and HEK293F cells, localizes to centrosomes but not to the Golgi apparatus (PubMed:29162697). .