U-Blot® Dorfin Polyclonal Antibody

Name: U-Blot® Dorfin Polyclonal Antibody
SKU: WP12058
Availability: InStock

$268.00

Size:50μL

SKU: WP12058-50

Catalog No.: WP12058

Specification: 50μL/100μL

Stock: In stock

U-Blot® Dorfin Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Product Overview

Catalog No.: WP12058
SKU: WP12058-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Dorfin
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 90kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human RNF19A. AA range:51-100
Sequence: --
Specificity: Dorfin Polyclonal Antibody detects endogenous levels of Dorfin protein.
Gene Name: RNF19A
Protein Name: E3 ubiquitin-protein ligase RNF19A
Other Name: RNF19A;RNF19;E3 ubiquitin-protein ligase RNF19A;Double ring-finger protein;Dorfin;RING finger protein 19A;p38
Organism-1: Human
Gene ID-1: 25897
SwissProt-1: Q9NV58
Organism-2: Mouse
Gene ID-2: 30945
SwissProt-2: P50636
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Membrane ; Multi-pass membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.