U-Blot® Dyskerin Polyclonal Antibody

Name: U-Blot® Dyskerin Polyclonal Antibody
SKU: WP12092
Availability: InStock

$268.00

Size:50μL

SKU: WP12092-50

Catalog No.: WP12092

Specification: 50μL/100μL

Stock: In stock

U-Blot® Dyskerin Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：dyskerin pseudouridine synthase 1(DKC1) Homo sapiens This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Product Overview

Catalog No.: WP12092
SKU: WP12092-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Dyskerin
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 57kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Dyskerin. AA range:171-220
Sequence: --
Specificity: Dyskerin Polyclonal Antibody detects endogenous levels of Dyskerin protein.
Gene Name: DKC1
Protein Name: H/ACA ribonucleoprotein complex subunit 4
Other Name: DKC1;NOLA4;H/ACA ribonucleoprotein complex subunit 4;CBF5 homolog;Dyskerin;Nopp140-associated protein of 57 kDa;Nucleolar protein NAP57;Nucleolar protein family A member 4;snoRNP protein DKC1
Organism-1: Human
Gene ID-1: 1736
SwissProt-1: O60832
Organism-2: Mouse
Gene ID-2: 245474
SwissProt-2: Q9ESX5
Organism-3: Rat
Gene ID-3: 170944
SwissProt-3: P40615
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Nucleus, nucleolus . Nucleus, Cajal body . Also localized to Cajal bodies (coiled bodies). .; [Isoform 3]: Cytoplasm .