U-Blot® FIR Polyclonal Antibody

Name: U-Blot® FIR Polyclonal Antibody
SKU: WP12310
Availability: InStock

$268.00

Size:50μL

SKU: WP12310-50

Catalog No.: WP12310

Specification: 50μL/100μL

Stock: In stock

U-Blot® FIR Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,

Product Overview

Catalog No.: WP12310
SKU: WP12310-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: FIR
Reactivity: Human,Mouse
Application: WB,IF,ELISA
MW(Calculated): --
MW(Observed): 119kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
Sequence: --
Specificity: FIR Polyclonal Antibody detects endogenous levels of FIR protein.
Gene Name: FARP2
Protein Name: FERM RhoGEF and pleckstrin domain-containing protein 2
Other Name: FARP2;KIAA0793;PLEKHC3;FERM;RhoGEF and pleckstrin domain-containing protein 2;FERM domain including RhoGEF;FIR;Pleckstrin homology domain-containing family C member 3;PH domain-containing family C member 3
Organism-1: Human
Gene ID-1: 9855
SwissProt-1: O94887
Organism-2: Mouse
Gene ID-2: 227377
SwissProt-2: Q91VS8
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: cytoplasm,cytosol,cytoskeleton,extrinsic component of membrane,