U-Blot® GCSc-γ Polyclonal Antibody

Name: U-Blot® GCSc-γ Polyclonal Antibody
SKU: WP12452
Availability: InStock

$268.00

Size:50μL

SKU: WP12452-50

Catalog No.: WP12452

Specification: 50μL/100μL

Stock: In stock

U-Blot® GCSc-γ Polyclonal Antibody Learn more

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Background：Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],

Product Overview

Catalog No.: WP12452
SKU: WP12452-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GCSc-γ
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 73kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GCSc-gamma. AA range:266-315
Sequence: --
Specificity: GCSc-γ Polyclonal Antibody detects endogenous levels of GCSc-γ protein.
Gene Name: GCLC
Protein Name: Glutamate--cysteine ligase catalytic subunit
Other Name: GCLC;GLCL;GLCLC;Glutamate--cysteine ligase catalytic subunit;GCS heavy chain;Gamma-ECS;Gamma-glutamylcysteine synthetase
Organism-1: Human
Gene ID-1: 2729
SwissProt-1: P48506
Organism-2: Mouse
Gene ID-2: 14629
SwissProt-2: P97494
Organism-3: Rat
Gene ID-3: 25283
SwissProt-3: P19468
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: cytosol,integral component of membrane,glutamate-cysteine ligase complex,