U-Blot® GLI-3 Polyclonal Antibody

Name: U-Blot® GLI-3 Polyclonal Antibody
SKU: WP12482
Availability: InStock

$268.00

Size:50μL

SKU: WP12482-50

Catalog No.: WP12482

Specification: 50μL/100μL

Stock: In stock

U-Blot® GLI-3 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP12482
SKU: WP12482-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GLI-3
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 14kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60
Sequence: --
Specificity: GLI-3 Polyclonal Antibody detects endogenous levels of GLI-3 protein.
Gene Name: GLI3
Protein Name: Transcriptional activator GLI3
Other Name: GLI3;Transcriptional activator GLI3;GLI3 form of 190 kDa;GLI3-190;GLI3 full length protein;GLI3FL
Organism-1: Human
Gene ID-1: 2737
SwissProt-1: P10071
Organism-2: Mouse
Gene ID-2: 14634
SwissProt-2: Q61602
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Cytoplasm. Cell projection, cilium. GLI3FL is localized predominantly in the cytoplasm while GLI3R resides mainly in the nucleus. Ciliary accumulation requires the presence of KIF7 and SMO. Translocation to the nucleus is promoted by interaction with ZIC1.