U-Blot® GPR143 Polyclonal Antibody

Name: U-Blot® GPR143 Polyclonal Antibody
SKU: WP12534
Availability: InStock

$268.00

Size:50μL

SKU: WP12534-50

Catalog No.: WP12534

Specification: 50μL/100μL

Stock: In stock

U-Blot® GPR143 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009],

Product Overview

Catalog No.: WP12534
SKU: WP12534-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GPR143
Reactivity: Human,Mouse
Application: IF,ELISA
MW(Calculated): 44kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications;
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200
Sequence: --
Specificity: GPR143 Polyclonal Antibody detects endogenous levels of GPR143 protein.
Gene Name: GPR143
Protein Name: G-protein coupled receptor 143
Other Name: GPR143;OA1;G-protein coupled receptor 143;Ocular albinism type 1 protein
Organism-1: Human
Gene ID-1: 4935
SwissProt-1: P51810
Organism-2: Mouse
Gene ID-2: 18241
SwissProt-2: P70259
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Melanosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .