U-Blot® GRK 4 Polyclonal Antibody

Name: U-Blot® GRK 4 Polyclonal Antibody
SKU: WP12614
Availability: InStock

$268.00

Size:50μL

SKU: WP12614-50

Catalog No.: WP12614

Specification: 50μL/100μL

Stock: In stock

U-Blot® GRK 4 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],

Product Overview

Catalog No.: WP12614
SKU: WP12614-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GRK 4
Reactivity: Human,Rat,Mouse,
Application: IHC,IF,ELISA
MW(Calculated): 67kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from GRK 4 . at AA range: 10-90
Sequence: --
Specificity: GRK 4 Polyclonal Antibody detects endogenous levels of GRK 4 protein.
Gene Name: GRK4
Protein Name: G protein-coupled receptor kinase 4
Other Name: GRK4;GPRK2L;GPRK4;G protein-coupled receptor kinase 4;G protein-coupled receptor kinase GRK4;ITI1
Organism-1: Human
Gene ID-1: 2868
SwissProt-1: P32298
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O70291
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Cytoplasm, cell cortex. Both at the cell surface and dispersed in the cytoplasm under basal conditions. Receptor stimulation results in the internalization of GRK4 to the perinuclear area, where colocalization with DRD3 is observed strongly at 5 and 15 minutes. DRD3 and GRK4 colocalize in lipid rafts of renal proximal tubule cells.