U-Blot® JAB1 Polyclonal Antibody

Name: U-Blot® JAB1 Polyclonal Antibody
SKU: WP12881
Availability: InStock

$268.00

Size:50μL

SKU: WP12881-50

Catalog No.: WP12881

Specification: 50μL/100μL

Stock: In stock

U-Blot® JAB1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP12881
SKU: WP12881-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: JAB1
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 38kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human COPS5. AA range:161-210
Sequence: --
Specificity: JAB1 Polyclonal Antibody detects endogenous levels of JAB1 protein.
Gene Name: COPS5
Protein Name: COP9 signalosome complex subunit 5
Other Name: COPS5;CSN5;JAB1;COP9 signalosome complex subunit 5;SGN5;Signalosome subunit 5;Jun activation domain-binding protein 1
Organism-1: Human
Gene ID-1: 10987
SwissProt-1: Q92905
Organism-2: Mouse
Gene ID-2: 26754
SwissProt-2: O35864
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Nuclear localization is diminished in the presence of IFIT3. .