U-Blot® Kpm Polyclonal Antibody

Name: U-Blot® Kpm Polyclonal Antibody
SKU: WP12943
Availability: InStock

$268.00

Size:50μL

SKU: WP12943-50

Catalog No.: WP12943

Specification: 50μL/100μL

Stock: In stock

U-Blot® Kpm Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP12943
SKU: WP12943-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Kpm
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): 120kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human LATS2. AA range:541-590
Sequence: --
Specificity: Kpm Polyclonal Antibody detects endogenous levels of Kpm protein.
Gene Name: LATS2
Protein Name: Serine/threonine-protein kinase LATS2
Other Name: LATS2;KPM;Serine/threonine-protein kinase LATS2;Kinase phosphorylated during mitosis protein;Large tumor suppressor homolog 2;Serine/threonine-protein kinase kpm;Warts-like kinase
Organism-1: Human
Gene ID-1: 26524
SwissProt-1: Q9NRM7
Organism-2: Mouse
Gene ID-2: 50523
SwissProt-2: Q7TSJ6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Colocalizes with AURKA at the centrosomes during interphase, early prophase and cytokinesis. Migrates to the spindle poles during mitosis, and to the midbody during cytokinesis. Translocates to the nucleus upon mitotic stress by nocodazole treatment.