U-Blot® MGMT Polyclonal Antibody

Name: U-Blot® MGMT Polyclonal Antibody
SKU: WP13159
Availability: InStock

$268.00

Size:50μL

SKU: WP13159-50

Catalog No.: WP13159

Specification: 50μL/100μL

Stock: In stock

U-Blot® MGMT Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WP13159
SKU: WP13159-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MGMT
Reactivity: Human,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 22kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
Sequence: --
Specificity: MGMT Polyclonal Antibody detects endogenous levels of MGMT protein.
Gene Name: MGMT
Protein Name: Methylated-DNA--protein-cysteine methyltransferase
Other Name: MGMT;Methylated-DNA--protein-cysteine methyltransferase;6-O-methylguanine-DNA methyltransferase;MGMT;O-6-methylguanine-DNA-alkyltransferase
Organism-1: Human
Gene ID-1: 4255
SwissProt-1: P16455
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P26187
Organism-3: Rat
Gene ID-3: 25332
SwissProt-3: P24528
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus.