U-Blot® MRCKα Polyclonal Antibody

Name: U-Blot® MRCKα Polyclonal Antibody
SKU: WP13228
Availability: InStock

$268.00

Size:50μL

SKU: WP13228-50

Catalog No.: WP13228

Specification: 50μL/100μL

Stock: In stock

U-Blot® MRCKα Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP13228
SKU: WP13228-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MRCKα
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 200kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from the Internal region of human MRCKα. AA range: 580-660
Sequence: --
Specificity: MRCKα Polyclonal Antibody detects endogenous levels of MRCKα protein.
Gene Name: CDC42BPA
Protein Name: Serine/threonine-protein kinase MRCK alpha
Other Name: CDC42BPA;KIAA0451;Serine/threonine-protein kinase MRCK alpha;CDC42-binding protein kinase alpha;DMPK-like alpha;Myotonic dystrophy kinase-related CDC42-binding kinase alpha;MRCK alpha;Myotonic dystrophy protein kinase-like alpha
Organism-1: Human
Gene ID-1: 8476
SwissProt-1: Q5VT25
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q3UU96
Organism-3: Rat
Gene ID-3: 114116
SwissProt-3: O54874
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell projection, lamellipodium . Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent. Localizes in the lamellipodium in a FAM89B/LRAP25-dependent manner. .