U-Blot® MRCKβ Polyclonal Antibody

Name: U-Blot® MRCKβ Polyclonal Antibody
SKU: WP13229
Availability: InStock

$268.00

Size:50μL

SKU: WP13229-50

Catalog No.: WP13229

Specification: 50μL/100μL

Stock: In stock

U-Blot® MRCKβ Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP13229
SKU: WP13229-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MRCKβ
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 194kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human MRCKB. AA range:1641-1690
Sequence: --
Specificity: MRCKβ Polyclonal Antibody detects endogenous levels of MRCKβ protein.
Gene Name: CDC42BPB
Protein Name: Serine/threonine-protein kinase MRCK beta
Other Name: CDC42BPB;KIAA1124;Serine/threonine-protein kinase MRCK beta;CDC42-binding protein kinase beta;CDC42BP-beta;DMPK-like beta;Myotonic dystrophy kinase-related CDC42-binding kinase beta;MRCK beta;Myotonic dystrophy protein kinase-like b
Organism-1: Human
Gene ID-1: 9578
SwissProt-1: Q9Y5S2
Organism-2: Mouse
Gene ID-2: 217866
SwissProt-2: Q7TT50
Organism-3: Rat
Gene ID-3: 113960
SwissProt-3: Q7TT49
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction . Cell projection, lamellipodium . Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent (By similarity). Detected at the leading edge of migrating cells. Localization at the leading edge of migrating cells requires interaction with catalytically active CDC42 (PubMed:21240187). Localizes in the lamellipodium in a FAM89B/LRAP25-dependent manner (By similarity). .