U-Blot® Nephrocystin-4 Polyclonal Antibody

Name: U-Blot® Nephrocystin-4 Polyclonal Antibody
SKU: WP13415
Availability: InStock

$268.00

Size:50μL

SKU: WP13415-50

Catalog No.: WP13415

Specification: 50μL/100μL

Stock: In stock

U-Blot® Nephrocystin-4 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Product Overview

Catalog No.: WP13415
SKU: WP13415-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Nephrocystin-4
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): 158kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human NPHP4. AA range:877-926
Sequence: --
Specificity: Nephrocystin-4 Polyclonal Antibody detects endogenous levels of Nephrocystin-4 protein.
Gene Name: NPHP4
Protein Name: Nephrocystin-4
Other Name: NPHP4;KIAA0673;Nephrocystin-4;Nephroretinin
Organism-1: Human
Gene ID-1: 261734
SwissProt-1: O75161
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P59240
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, tight junction . Nucleus . In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions (By similarity). Localizes to the ciliary transition zone (By similarity). In the retinal photoreceptor cell layer, localizes at the connecting cilium (By similarity). .