U-Blot® Neuregulin-1 SMDF Polyclonal Antibody

Name: U-Blot® Neuregulin-1 SMDF Polyclonal Antibody
SKU: WP13425
Availability: InStock

$268.00

Size:50μL

SKU: WP13425-50

Catalog No.: WP13425

Specification: 50μL/100μL

Stock: In stock

U-Blot® Neuregulin-1 SMDF Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016],

Product Overview

Catalog No.: WP13425
SKU: WP13425-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Neuregulin-1
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 44kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50
Sequence: --
Specificity: Neuregulin-1 SMDF Polyclonal Antibody detects endogenous levels of Neuregulin-1 SMDF protein.
Gene Name: NRG1
Protein Name: Pro-neuregulin-1 membrane-bound isoform
Other Name: Pro-neuregulin-1 membrane-bound isoform;Pro-NRG1;NRG1;GGF;HGL;HRGA;NDF;SMDF
Organism-1: Human
Gene ID-1: 3084
SwissProt-1: Q02297-10
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Does not seem to be active.; [Neuregulin-1]: Secreted.; [Isoform 8]: Nucleus. May be nuclear.; [Isoform 9]: Secreted. Has a signal peptide.; [Isoform 10]: Membrane; Single-pass type I membrane protein. May possess an internal uncleaved signal sequence.