U-Blot® Nogo A Polyclonal Antibody

Name: U-Blot® Nogo A Polyclonal Antibody
SKU: WP13505
Availability: InStock

$268.00

Size:50μL

SKU: WP13505-50

Catalog No.: WP13505

Specification: 50μL/100μL

Stock: In stock

U-Blot® Nogo A Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP13505
SKU: WP13505-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Nogo A
Reactivity: Human,Mouse,Rat
Application: WB,IHC,ELISA
MW(Calculated): --
MW(Observed): 220kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Nogo A. AA range:450-499
Sequence: --
Specificity: Nogo A Polyclonal Antibody detects endogenous levels of Nogo A protein.
Gene Name: RTN4
Protein Name: Reticulon-4
Other Name: RTN4;KIAA0886;NOGO;My043;SP1507;Reticulon-4;Foocen;Neurite outgrowth inhibitor;Nogo protein;Neuroendocrine-specific protein;NSP;Neuroendocrine-specific protein C homolog;RTN-x;Reticulon-5
Organism-1: Human
Gene ID-1: 57142
SwissProt-1: Q9NQC3
Organism-2: Mouse
Gene ID-2: 68585
SwissProt-2: Q99P72
Organism-3: Rat
Gene ID-3: 83765
SwissProt-3: Q9JK11
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform A]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane; Multi-pass membrane protein ; Cytoplasmic side . Anchored to the membrane of the endoplasmic reticulum (ER) through 2 putative transmembrane domains. Localizes throughout the ER tubular network (PubMed:27619977). Co-localizes with TMEM33 at the ER sheets. .; [Isoform B]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein ; Extracellular side . Cell junction . Mainly located on endoplasmic reticulum tubules and sheet edges (PubMed:27786289). Upon ICAM1 engagement, redistributed toward endothelial junctions where interacts with CDH5 (PubMed:21183689). .; [Isoform C]: Endoplasmic reticulum membrane ; Multi-pass membrane protein .