U-Blot® Nrf2 Polyclonal Antibody

Name: U-Blot® Nrf2 Polyclonal Antibody
SKU: WP13528
Availability: InStock

$268.00

Size:50μL

SKU: WP13528-50

Catalog No.: WP13528

Specification: 50μL/100μL

Stock: In stock

U-Blot® Nrf2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WP13528
SKU: WP13528-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Nrf2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): 68kD
MW(Observed): 75-100kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Nrf2. AA range:556-605
Sequence: --
Specificity: Nrf2 Polyclonal Antibody detects endogenous levels of Nrf2 protein.
Gene Name: NFE2L2
Protein Name: Nuclear factor erythroid 2-related factor 2
Other Name: NFE2L2;NRF2;Nuclear factor erythroid 2-related factor 2;NF-E2-related factor 2;NFE2-related factor 2;HEBP1;Nuclear factor;erythroid derived 2, like 2
Organism-1: Human
Gene ID-1: 4780
SwissProt-1: Q16236
Organism-2: Mouse
Gene ID-2: 18024
SwissProt-2: Q60795
Organism-3: Rat
Gene ID-3: 83619
SwissProt-3: O54968
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Nucleus . Cytosolic under unstressed conditions: ubiquitinated and degraded by the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:15601839, PubMed:21196497). Translocates into the nucleus upon induction by electrophilic agents that inactivate the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:21196497). .