U-Blot® SYNE2 Polyclonal Antibody

Name: U-Blot® SYNE2 Polyclonal Antibody
SKU: WP1367
Availability: InStock

$268.00

Size:50μL

SKU: WP1367-50

Catalog No.: WP1367

Specification: 50μL/100μL

Stock: In stock

U-Blot® SYNE2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Product Overview

Catalog No.: WP1367
SKU: WP1367-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SYNE2
Reactivity: Human,Mouse
Application: IHC,IF
MW(Calculated): --
MW(Observed): 757kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-300;IF 1:50-200
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 360-440
Sequence: --
Specificity: SYNE2 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: SYNE2 KIAA1011 NUA
Protein Name: Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Other Name: --
Organism-1: Human
Gene ID-1: 23224
SwissProt-1: Q8WXH0
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6ZWQ0
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus outer membrane ; Single-pass type IV membrane protein ; Cytoplasmic side . Sarcoplasmic reticulum membrane ; Single-pass type IV membrane protein . Cell membrane ; Single-pass membrane protein . Cytoplasm, cytoskeleton. Mitochondrion. Nucleus, nucleoplasm. Cytoplasm, myofibril, sarcomere, Z line . Different isoform patterns are found in the different compartments of the cell. The isoforms having the C-terminal transmembrane span can be found in several organellar membranes like the nuclear envelope, the sarcoplasmic reticulum of myoblasts, or the lamellipodia and focal adhesions at the cell membrane. The largest part of the outer nuclear membrane-associated protein is cytoplasmic, while its C-terminal part is associated with the nuclear envelope, most probably the outer nuclear membrane. Remains associated with the nuclear envelope during its breakdown in mitotic cells. Shorter soluble isoforms can be found in the cytoplasm and within the nucleus.; [Isoform 8]: Cell junction, focal adhesion . In U2OS cells. .