U-Blot® PCAF Polyclonal Antibody

Name: U-Blot® PCAF Polyclonal Antibody
SKU: WP13891
Availability: InStock

$268.00

Size:50μL

SKU: WP13891-50

Catalog No.: WP13891

Specification: 50μL/100μL

Stock: In stock

U-Blot® PCAF Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP13891
SKU: WP13891-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PCAF
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 93kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human p300/CBP. AA range:783-832
Sequence: --
Specificity: PCAF Polyclonal Antibody detects endogenous levels of PCAF protein.
Gene Name: KAT2B
Protein Name: Histone acetyltransferase KAT2B
Other Name: KAT2B;PCAF;Histone acetyltransferase KAT2B;Histone acetyltransferase PCAF;Histone acetylase PCAF;Lysine acetyltransferase 2B;P300/CBP-associated factor;P/CAF
Organism-1: Human
Gene ID-1: 8850
SwissProt-1: Q92831
Organism-2: Mouse
Gene ID-2: 18519
SwissProt-2: Q9JHD1
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Mainly localizes to the nucleus. Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation. Subcellular location may vary depending upon cell differentiation state. Cytoplasmic at the very stages of keratinocyte differentiation, becomes nuclear at later differentiation stages. Cytoplasmic in basal epithelial cells (undifferentiated cells) and nuclear in parabasal cells (differentiated cells) (PubMed:20940255). .